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Researcher

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William Bauer, Ph.D.

Manager

Research Areas:

Biography:
Dr. William F. Bauer is manager of the Chemical and Radiation Measurements Department at Idaho National Laboratory. The department is comprised of 28 staff members of all experience and education levels from doctorate to technician. It is responsible for conducting basic research, applied research, method development and routine work in the areas of environmental chemistry, radioanalytical chemistry, gamma spectroscopy, molecular spectroscopy, atomic spectroscopy, chromatography, mass spectrometry, isotope ratio measurements and other general analytical support for research and operational activities at the INL. Bauer earned his doctorate in analytical chemistry at University of Idaho. He holds bachelor’s degrees in biology and chemistry from Chardron State College.

Education:

​Ph.D., Analytical Chemistry - University of Idaho

B.A., Biology and Chemistry - Chadron State University

Affiliations:

​American Chemical Society
Society for Applied Spectroscopy
International Society for Neutron Capture Therapy

Publications:

​Heber, E. M.; Kueffer, P. J.; Lee, M. W.; Hawthorne, M. F.; Garabalino, M. A.; Molinari, A. J.; Nigg, D. W.; Bauer, W.; Hughes, A. M.; Pozzi, E. C. C.; Trivillin, V. A.; Schwint, A. E. "Boron delivery with liposomes for boron neutron capture therapy (BNCT): biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential", Radiation and Environmental Biophysics 2012, 51, 195-204.

 

Swancutt, K. L.; Cullen, T. D.; Mezyk, S. P.; Elias, G.; Bauer, W. F.; Ball, R. D.; Peterman, D. R.; Riddle, C. L.; Mincher, B. J.; Muller, J. J. "The Radiation Chemistry of the Cs-7SB Modifier used in Cs and Sr Solvent Extraction", Solvent Extraction And Ion Exchange 2011, 29, 106-127.

 

Stone, M. L.; Orme, C. J.; Peterson, E. S.; Bauer, W. F.; Stewart, F. F.; Harrup, M. K.; Luther, T. A.; Klaehn, J. R.; Wey, J. E. "Water Transport Polymers - Structure/Property Relationships of a Series of Phosphazene Polymers", Separation Science and Technology 2010, 45, 1880-1885.


B.J. Mincher, S.P. Mezyk, W.F. Bauer, G. Elias, C. Riddle and D.R. Peterman, ”FPEX Gamma-Radiolysis In The Presence Of Nitric Acic” Solvent Extraction and Ion Exchange, 2007, 25(5), 593-601.

 

G.S. Groenewold, M.M. Cortez, A.K. Gianotto, G.L. Gresham, J.E. Olson, R.V. Fox, B.M. White, W.F. Bauer, R. Avci, M. Deliorman, and E. Williams, “Surface Analysis Of Particulates From Laboratory Hood Exhaust Manifold”, Surface and Interface Analysis, 2007, 39, 547-553.

 

W.F. Bauer, M.L. Stone, C.J. Orme, M.K. Harrup, and T.A. Luther, “Infrared Spectroscopic Measurement Of Water Permeability In Polymer Films Exposed To Liquid Water”, Polymer Testing, 2006, 25(5), 642-649.

 

Elias, G. and W. F. Bauer. "Hydrazine Determination In Sludge Samples By High-Performance Liquid Chromatography." Journal Of Separation Science, 2006, 29(3): 460-464.

 

Elias, G., W. F. Bauer, J. G. Eisenmenger, C. C. Jensen, B. K. Schuetz, T. C. Sorensen, B. M. White, A. L. Freeman and M. E. Mc Ilwain.  Amchitka Island Environmental Analysis at Idaho National Laboratory. INL/EXT-05-00361. Idaho National Laboratory, Idaho Falls, ID. 2005, 500 pp.

 

G.S. Groenewold, W.F. Bauer, R.V. Fox, B.J. Mincher, and A.K. Gianotto, “Actinide Analysis and Leaching of Samples Collected from the Glovebox Excavator Method Project for OU 7-13/14”, ICP/EXT-04-00439, April 2005.

 

W.F. Bauer and G.S. Groenewold, “Elemental Analysis of Series 2004 Twenty Dollar Notes”, INEEL/EXT-04-02146, July 2004.


T. Ozawa, R.A. Santos, K.R. Lamburn, W.F. Bauer, M-S. Koo, S.B. Kahl, and D.F. Deen, “In Vivo Evaluation of the Boronated Porphyrin TABP-1 in U-87 MG Intracerebral Human Glioblastoma Xenografts”, Molecular Pharmaceutics, 2004, 1 (5), 368-374.

 

T. A. Luther, F. F. Stewart, J. L. Budzien, R. A. LaViolette, W. F. Bauer, M. K. Harrup, C. W. Allen, and A. Elayan, “On the Mechanism of Ion Transport Through Polyphosphazene Solid Polymer Electrolytes: NMR, IR, and Raman Spectroscopic Studies and Computational Analysis of 15N Labeled Polyphosphazenes,” Journal of Physical Chemistry B, 2003, 107, 3168-3176.

 

J.C. Ingram, W.F. Bauer, R.M. Lehman, S.P. O’Connell, and A.D. Shaw, “Detection of Fatty Acids from Intact Microorganisms by Molecular Beam Static Secondary Ion Mass Spectrometry”, Journal of Microbiological Methods, 2003, 53, 295-307.

 

W.F. Bauer, “Applications of Infrared Spectroscopy for the Determination of Boron in Biological Samples”,  In: Research and Developments in Neutron Capture Therapy, W. Sauerwein, R. Moss and A. Wittig, eds, Monduzzi Editore, Bologna, Italy, 2002, pp 943-947.

 

S.E. O’Brien, J.A. McLean, B.W. Acon, B.J. Eshelman, W.F. Bauer, and A. Montaser, “Determination of Memory Prone Elements Using Direct Injection High Efficiency Nebulizer-Inductively Coupled Plasma Mass Spectrometry”, Applied Spectroscopy, 2002, 56, 1006-12.

 

J.H. Goodman, W. Yang, R.F. Barth, Z. Gao, C.P. Boesel, A.E. Staubus, N. Gupta, R.A. Gahbauer, D.M. Adams, C.R. Gibson, A.K. Ferketich, M.L. Moeschberger, A.H. Soloway, D.E. Carpenter, W.F. Bauer, M.Z. Zhang, and C.C. Wang, “Boron Neutron Capture Therapy of Brain Tumors: Biodistribution, Pharmacokinetics and Radiation Dosimetry of Sodium Borocaptate in Glioma Patients”, J. Radiation Oncology, 2000, 47(3), 608-621.

 

Jay Tibbitts, Nancy C. Sambol, John R. Fike, William F. Bauer, Stephen B. Kahl, “Plasma Pharmacokinetics and Tissue Biodistribution of Boron Following Administration of a Boronated Porphyrin in Dogs”, Journal of Pharmaceutical Sciences, 2000, 89(4), 469-477.

 

G.L. Gresham, G.S. Groenewold, W.F. Bauer, J.C. Ingram, “Secondary Ion Mass Spectrometry Characterization Of Nail Polish and Paint Surfaces”, J. Forensic Science, 2000, 45(2), 310-323.

 

D.E. Callahan, T.M. Forte, S.M. Javed Afzal, D.F. Deen, S.B. Kahl, K.A. Bjornstad, W.F. Bauer and E.A. Blakely, “Boronated Protoporphyrin (BOPP): Localization in Lysosomes of the Human Glioma Cell Line SF-767 with Uptake Modulated by Lipoprotein Levels”, Int. J. Rad. Onc. Biol. Phys, 1999, 45(3), 761-771.

 

W.F. Bauer, M.J. Connolly, A. Rilling, D. Gravel, and S. Perry, “Evaluation of Fourier Transform Infrared Spectroscopy for the Determination of Volatile Organic Compounds in Transuranic Waste Drum Headspace”, Idaho National Engineering Laboratroy, INEL-95/0332, September 7, 1995. (Reviewed by 4 outside experts in infrared spectroscopy)

 

W.F. Bauer, G.L. Gresham, and A.K. Gianotto, “Additional Impurities Identified in Borocaptate Sodium”, in: Cancer Neutron Capture Therapy, Y. Mishima, ed., Plenum, New York, 1996, pp. 643-648.

P-P,P Zhu Tang, M.P. Schweizer, K.M. Bradshaw, and W.F. Bauer, “11B Studies of the Interaction of Borocaptate Sodium with Serum Albumin”, Biochemical Pharmacology, 1995, 49(5), 625-632.

 

T.R. LaHaan, W.F. Bauer, P.R. Gavin, and D.R. Lu, "Pharmacokinetics and Toxicity of a p-Boronophenylalanine-Cyclodextrin Formulation Delivered by Intravenous Infusion to Dogs," Chapter 6 in: Polymeric Drugs and Drug Delivery Systems, R. Ottenbrite, ed., American Chemical Society,  Washington D.C., 1994, pp 66-78.

 

S.L. Kraft, P.R. Gavin, C.W. Leathers, C.E. DeHaan, W.F. Bauer, D.L. Miller, and R.V. Dorn III, "Biodistribution of Boron in Dogs withg Spontaneous Intracranial Tumors Following Borocaptate Sodium Adminstration", Cancer Research, 1994, 54(5), 1259-1263.

 

W. F. Bauer, P. Micca, and B.M. White, "A Rapid Method for the Direct Analysis of Boron in Whole Blood by Atomic Emission Spectroscopy", in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, pp 403-407.

 

A.K. Gianotto and W.F. Bauer, "Purity and Quality Determinations of Sodium Borocaptate", in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, 459-463.

 

N.J. Hotz and W.F. Bauer, "Determination of Sodium Borocaptate Binding Blood Serum Protein Fractions by HPLC Coupled to an ICP-AES", in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, pp 439-443.

 

V.K.F. Chia, R.J. Bleiler, D.B. Sams, C.M. Jones, R.W. Odom, W.F. Bauer, A.K. Gianotto, C.D. Swartz, and J.P. Weidner, "Quantification of Boron in Biological Tissue by Secondary Ion Mass Spectrometry", in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, 409-412.

 

D.A. Feakes, K.J. Shelly, M.F. Hawthorne, P.G. Schmidt, C.A. Elstad, G.G. Meadows, and W.F. Bauer, "Liposomal Delivery of Boron to Murine Tumors for Boron Neutron Capture Therapy," in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, pp 395-398.

 

C.A. Elstad, K.R. Meinkoth, B.A. Mathison, G.G. Meadows, D.H. Kinder, M.F. Hawthorne, K.J. Shelly,  D.A. Feakes and W.F. Bauer, "In Vivo and In Vitro Uptake of Boronated Compounds by B16-BL6 Murine Melanoma," in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, pp 619-622.

 

T.R. LaHaan, R.D. Lu, G. Daniell, S.L. Kraft, P.R. Gavin, and W.F. Bauer, "Bioavailability of Intravenous Formulations of p-Boronophenylalanine in Dog and Rat," in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, pp 585-589.

 

P.R. Gavin, C.E. DeHaan, M.P. Moore, J.P. Weidner, C.D. Swartz, S.L. Kraft, C.A. Atkinson, C.R. Amaro, W.F. Bauer, and A. Siefert, "Large Animal Studies on the Use of BNCT for the Treatment of Brain Tumors," in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, 469-475.

 

P-P.Z. Tang, M.P. Schweizer, W.F. Bauer and K.M. Bradshaw, "NMR Studies of the Interaction of Borocaptate Sodium with Serum Albumin," in: Advances in Neutron Capture Therapy, A.H. Soloway, R.F Barth and D.E. Carpenter, eds., Plenum Press, NY, 1993, 453-457.

 

D.A. Johnson, D.D. Siemer, and W.F. Bauer, "An ICP-AES Method for Determination of Low Level Boron in Milligram Sized Tissue Samples." Analytica Chimica Acta, 1992, 270, 223-30.

 

J.M. Moran, D.W. Nigg, F.J. Wheeler, and W.F. Bauer, "Macroscopic Geometric Heterogeneity Effects in Radiation Dose Distribution Analysis for Boron Neutron Capture Therapy," Medical Physics, 1992, 19(3), 723-732.

 

W.F. Bauer, K.M. Bradshaw, and T.L. Richards, "Interactions Between Boron Containing Compounds and Serum Albumin Observed by Nuclear Magnetic Resonance," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 339-343.

 

A.K. Gianotto and W.F. Bauer, "Enantiomeric Separation of D,L-p-Boronophenylalanine by High Performance Liquid Chromatography with a Chiral Mobile Phase," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 247 250.

 

W.F. Bauer, J.W. Wishard, C. Rae and N. Lassahn, "Flow Injection for Sample Introduction Into Inductively Coupled Plasmas for the Determination of Boron in Biological Samples," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 297-300.

 

S.L. Kraft, P.R. Gavin, C.E. DeHaan, W.F. Bauer, T.E. Ary, "The Biodistribution of Boron in Normal Canine Tissues Following Borocaptate Sodium Administration and the Effect of Plasma Exchange," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 489-492.

 

P.R. Gavin, S.L. Kraft, C.E. DeHaan, R.D. Sande, M. Papageorges, W.F. Bauer, "Spontaneous Canine Oral Melanoma:  A Large Animal Model for BNCT," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 411-416.

 

M. Papageorges, C.A. Elstad, G.G. Meadows, P.R. Gavin, R.D. Sande and W.F. Bauer, "Studies on the Uptake of Para-Boronophenylalanine in Melanoma Cells," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 373-376.

 

R.V. Dorn III, M.L. Griebenow, A.L. Ackerman, L.G. Miller, P.R. Gavin, D.L. Miller F.J. Wheeler, K.M. Bradshaw, T.L. Richards, D.E. Wessol, Y.D. Harker, D.W. Nigg, P.D. Randolph, and W.F. Bauer, "The Idaho Power Burst Facility/Boron Neutron Capture Therapy (PBF/BNCT) Program Overview," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 13-20.

 

S.L. Kraft, P.R. Gavin, C.E. DeHaan, C.W. Leathers, W.F. Bauer, and R.V. Dorn III, "The Biodistribution of Boron in Canine Spontaneous Intracranial Tumors Following Borocaptate Sodium Infusion," in: Progress in Neutron Capture Therapy for Cancer, B. J. Allen et. al. eds, Plenum Press, New York 1992, pp 537-540.

 

W.F. Bauer, D.A. Johnson, S.M. Steele, K. Messick, D.L. Miller, and W.A. Propp, "Gross Boron Determination in Biological Samples by Inductively Coupled Plasma Atomic Emission Spectroscopy."  Strahlentherapie und Onkologie, 1989, 165, 176 179.

 

B. Bauer and T. F. Brown, "The measurement of Glucose in Biological Fluids using FTIR CIR."  Analytica Chimica Acta, 1987, 197, 295 301.

Patents:

​R.L. Hoskinson, J.M. Svoboda, W.F. Bauer, and G. Elias, 2008, “Method and apparatus for monitoring characteristics of a flow path having solid components flowing therethrough,” Patent 7,367,880, May 6, 2008.

Presentations:

​D.L. Stoner, W. Bauer, C. B. Pilcher and L. A. Todd (2004). "Spectroscopic Study of Volatile Biogenic Signatures Emanating from Geothermal Environments." Abstracts Of Papers Of The American Chemical Society, 2004, 228, U696-U696.

 

T.A. Dunder and W.F. Bauer, "Characterization of Radioactive Waste for Permanent Disposal at the Waste Isolation Pilot Plant by On-Site FTIR Gas Headspace Analysis of Transuranic Waste Containers", Proceedings of the 14th International Symposium on the Measurement of Toxic and Related Air Pollutants held September 12-14, 2000, Research Triangle Park, NC.

 

W.F. Bauer, C.A. Crowder, R.E. Evans, and T. Dunder, “Assessment of the Performance of Fourier Transform Infrared Spectroscopy for the Determination of Volatile Organic Compounds in Waste Drum Headspace”, Proceedings of The 15th Annual Waste Testing and Quality Assurance Symposium, Arlington, VA, July 18-22, 1999, 15-20. (see also http://www.epa.gov/epaoswer/hazwaste/test/pdfs/final99.pdf)

 

W.F. Bauer, M.J. Connolly, D. Gravel, A. Rilling, and F. Baudais, “Implementation of a Fourier Transform Infrared Spectrophotometer for the Determination of VOC s in Waste Drum Headspace”, Proceedings of The Tenth Annual Waste Testing and Quality Assurance Symposium, Arlington, VA, July 11-15, 1994, pp 758-772.


E.S. Peterson, M.L. Stone, W.F. Bauer and A.K. Gianotto, "The Removal of Organic Chemicals from Waste Streams using Polyphosphazene Membranes," Recents Progr. Genie Procedes (Membrane Processes: Water Treatment-Pervaporation), 1992, 6(21), 381-387, Euromembrane 92-Paris, Paris France.

 

S.L. Kraft, P.R. Gavin, C.E. DeHaan, C.W. Leathers, W.F. Bauer, D.L. Miller, and R.V. Dorn III, "Borocaptate Sodium:  A Potential Boron Delivery Compound for Boron Neutron Capture Therapy Evaluated in Dogs with Spontaneous Intracranial Tumors", Proceeding of the National Academy of Sciences,  1992, 89, 11973-11977.

 

K. Shelly, D.A. Feakes, M.F. Hawthorne, P.G. Schmidt, T.A. Krisch and W.F. Bauer, "Model Studies Directed Toward the Boron Neutron Capture Therapy of Cancer:  Boron Delivery to Murine Tumors with Liposomes," Proceedings of the National Academy of Sciences, 1992, 89(19), 9039-9043.

Version: 3.0
Created at 7/10/2017 2:25 PM by Phyllis L. King
Last modified at 7/10/2017 2:46 PM by Phyllis L. King